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  5. Christine Risso - Assistant Professor
Christine Risso - Assistant Professor
christinerisso
(Eco)Toxicology - (Eco)Physiology - Environmental Stress - Aquatic environment - Risk assessment - Environmental Directives and Regulations
(Eco)Toxicology - (Eco)Physiology - Environmental stress - Aquatic Environment - Biomarkers - Biotest development - Cell and molecular signalling - Bioindicators - Biomonitoring
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christine.risso[at]unice.fr

Since 2003, I am an Assistant Professor at the University of Nice-Sophia Antipolis, and attached to ECOMERS laboratory since 2008. My main research focuses on the understanding of responses of aquatic (marine and freshwater) organisms (fish and invertebrate organisms) to different environmental stress (pollutions, climate change), through the study of different defense and adaptation mechanims. My objectives are to develop and validate the new and relevant biomarkers in response to a specific or global stress, at different levels of biological organization (molecular, cellular, individu), in order to predict the potential effects at the populational level and the ecosystem. I work also in developping the in vitro bioassays to identify and assess the specific effects of chemicals on human and environmental health (e.g. endocrine disruption, genotoxicity, immunotoxicity). I am also involved in developping of the bioinformatic modelization tools for toxicological assessment.


 

 Publications (international journals):

 Benaïssa, M., Rouane-Hacene O., Boutiba Z., Habib D., Guibbolini-Sabatier M., Risso-de Faverney C. 2017. Ecotoxicological impact assessment of the brine discharges from a desalination plant in the marine waters of the Algerian west coast, using a multibiomarker approach in a limpet, Patella rustica. Environmental Science and Pollution Research. (doi: 10.1007/s11356-017-0081-4).
 Rouane-Hacene O., Boutiba Z., Benaïssa M., Belhaouari B., Francour P., Guibbolini-Sabatier M., Risso-de Faverney C. 2017.Seasonal assessment of biological indices, bioaccumulation and bioavailability of heavy metals in sea urchins Paracentrotus lividus from Algerian west coast, applied to environmental monitoring. Environmental Science and Pollution Research, 24 (212), 1-14. (doi: 10.1007/s11356-017-8946-0.)
 Rouane-Hacene O., Boutiba Z., Belhaouari B., Guibbolini-Sabatier M., Francour P., Risso-de Faverney C. 2015. Seasonal assessment of biological indices, bioaccumulation and bioavailability of heavy metals in mussels Mytilus galloprovincialis from Algerian west coast, applied to environmental monitoring. Oceanologia, 57, 362-375.
 Buffet PE, Zalouk-Vergnoux A, Poirier L, Lopes C, Risso-de-Faverney C, Guibbolini M, Gilliland D, Perrein-Ettajani H, Valsami-Jones E, Mouneyrac C. 2015. Cadmium sulfide quantum dots induce oxidative stress and behavioral impairments in the marine clam Scrobicularia plana.Environmental Toxicology and Chemistry, 34(7):1659-64.
 Dallot C., Blanck O., Hilmi C., Bars R., Risso-de Faverney C. 2014. In vitro screening of thyroid function disruption: PC-Cl3 cell line, a promising tool. Toxicology Letters, Vol. 229 : S137.
Mouneyrac C., Buffet, P.E, Poirier L., Zalouk-Vergnoux A., Guibbolini, M., Risso-Faverney, C, Gilliland, D.,Berhanu, D., Dybowska, A., Châtel A., Perrein-Ettajni, H., Pan, J.F., Thomas-Guyon, H., Reip, P., Valsami-Jones E. 2014. Fate and effects of metal-based nanoparticles in two marine invertebrates, the bivalve mollusk Scrobicularia plana and the annelid polychaete Hediste diversicolor. Environmental Science and Pollution Research, 21(13):7899-912.(IF 2015 = 2,760)
Buffet P.-E., Poirier L., Zalouk-Vergnoux A., Lopes C., Amiard J.C., Gaudin P., Risso-de Faverney C., Guibbolini M., Gilliland D., Perrein-Ettajani H., Valsami-Jones E., Mouneyrac C. 2014. Biochemical and behavioural responses of the marine polychaete Hediste diversicolor to cadmium sulfide quantum dots (CdS QDs): Waterborne and dietary exposure. Chemosphere, 100 : 63-70.
Buffet, P.E, Vergnoux A., Châtel A., Berthet B., Métais I., Perrein H., Poirier L., Luna-Acosta A., Thomas-Guyon H., Risso-Faverney, C, Guibbolini, M., Gililand D., Valsami-Jones, E., Mouneyrac, C. 2014. A marine mesocosm study on the environmental fate of silver nanoparticles and toxicity effects on two endobenthic species: the ragworm Hediste diversicolor and the bivalve mollusc Scrobicularia plana. Science of the Total Environment, 470-471 : 1151-1159.
Nouira, T., Risso, C., Lassaad, C., Budzinski, H., Boussetta, H. 2013 Polychlorinated Biphenyls (PCBs) and Polybrominated Diphenyl Ethers (PBDEs) in surface sediments from Monastir Bay (Tunisia Central Mediterranean): occurrence, distribution and seasonal variation. Chemosphere, 93: 487−493.
Buffet, P.E, Richard, M., Caupos, F., Vergnoux, A., Perrein-Ettajani, H., Luna-Acosta, A., Akcha, F., Amiard, J.C., Amiard-Triquet, C., Guibbolini, M., Risso-Faverney, C, Thomas-Guyon, H., Reip, P., Dybowska, A., Berhanu, D., Valsami-Jones, E., Mouneyrac, C. 2013. A mesocosm study of fate and effects of CuO nanoparticles on endobenthic species (Scrobicularia plana, Hediste diversicolor). Environmental Science & Technology, 47: 1620−1628.
Buffet, P.E, Pan,J.F., Poirier, L., Amiard-Triquet, C., Gaudin, P., Risso-Faverney, C, Guibbolini, M., Gilliland, D., Valsami-Jones, E., Mouneyrac C. 2013. Biochemical and behavioural responses of the endobenthic bivalve Scrobicularia plana to silver nanoparticles in seawater and microalgal food. Ecotoxicology and Environmental Safety, 89 : 117-124.
Buffet, P.E, Amiard-Triquet, C., Dybowska, A., Risso-Faverney, C, Guibbolini, M., Valsami-Jones, E., Mouneyrac C., 2012. Fate of isotopically labeled zinc oxide nanoparticles in sediment and effects on two endobenthic species, the clam Scrobicularia plana and the ragworm Hediste diversicolor. Ecotoxicology and Environmental Safety, 84, 191-198.
Pan J.F., Buffet P.E., Poirier L., Amiard-Triquet C., Gilliland,D., Joubert Y., Pilet P., Guibbolini, M., Risso-de Faverney,C., Roméo, M., Valsami-Jones, E., Mouneyrac C, 2012. Size Dependent Bioaccumulation and Ecotoxicology of Gold Nanoparticles in an Endobenthic Invertebrate: the Tellinid Clam Scrobicularia plana.Environmental Pollution, 166, 37-43.
Buffet P.E., Tankoua-Fossi, O., Pan, J.F., Berhanu D., Herrenknecht C., Poirier L., Amiard-Triquet C., Amiard J.C., Bérard J.B., Risso-de Faverney C., Guibbolini M., Roméo M., Reip P., Valsami-Jones E., Mouneyrac C., 2011. Behavioural and biochemical responses of two marine invertebrates Scrobicularia plana and Nereis diversicolor to copper oxide nanoparticles. Chemosphere, 84, 166-174.
Risso-de Faverney C., Guibbolini-Sabatier M., Francour P., 2010. An ecotoxicological approach with transplanted mussels (Mytilus galloprovincialis) for assessing the impact of tyre reefs immersed along the NW Mediterranean Sea. Marine Environmental Research, 70, 87-94.
Risso-de Faverney C., Orsini, N., de Sousa, G., Rahmani, R., 2004. Cadmium-induced apoptosis through the mitochondrial pathway in rainbow trout hepatocytes: involvement of oxidative stress, Aquatic Toxicology, 69, 249-258.
Risso-de Faverney C., Devaux A., Lafaurie M., Girard JP., Rahmani, R., 2001. Toxic effects of wastewaters collected on upstream and downstream sites of a purification station in cultures of rainbow trout (Oncorhynchus mykiss) hepatocytes, Archives of Environmental Contamination and Toxicology, 41(2), 129-141.
Risso-de Faverney C., Devaux A., Lafaurie M., Girard JP., Bailly B., Rahmani, R., 2001. Cadmium induces apoptosis and genotoxicity in trout (Oncorhynchus mykiss) hepatocyte cultures by generation of reactive oxygene species, Aquatic Toxicology, 53(1), 65-76.
Risso-de Faverney C., Lafaurie M., Girard JP., Rahmani, R., 2000. Effects of heavy metals and 3-methylcholanthrene on expression and induction of CYP1A1 and metallothionein levels in trout (Oncorhynchus mykiss) hepatocyte cultures, Environmental Toxicology and Chemistry, 19(5), 2239-2248.
Risso-de Faverney C., Lafaurie M., Girard JP., Rahmani, R., 2000. The nitroxide stable radical TEMPO prevents metal-induced inhibition of CYP1A1 expression and induction, Toxicological Letters, 111, 219-227.
Risso-de Faverney C., de Sousa G., Lafaurie M., Rahmani, R., 1999. Expression and induction of CYP1A1 in black seabream (Spondyliosoma cantharus) hepatocyte cultures, Polycyclic Aromatic Compounds, 13, 285-299
Stien X., Risso C., Gnassia-Barelli M., Romeo M., Lafaurie M., 1997. Effect of copper chloride in vitro and in vivo on the hepatic EROD activity in the fish Dicentrarchus labrax, Environmental Toxicology and Chemistry, 16, 2, 214-219.
Romeo M., Cosson R.P., Gnassia-Barelli M., Risso C., Stien X., Lafaurie M., 1997. Metallothionein determination in the liver of the sea bass Dicentrarchus labrax treated with copper and B(a)P, Marine Environmental Research, 44, 3, 275-284.

Publications (in non-indexed journals):

Miraglio B., Bernot G., Comet J-C, Risso-de Faverney C. 2017. Detecting Toxicity Pathways with a Formal Framework based on Equilibrium Changes. In : Proceedings of the 15th International Conference on Computational Methods in Systems Biology (CMSB 2017) - 27-29 September 2017, Darmstadt, Germany.
Miraglio B., Bernot G., Comet J-C, Risso-de Faverney C. 2017. A qualitative Framework dedicated to Toxicology. Topics: Computational Molecular Systems; Simulation and Modeling : Systems Biology In : Proceedings of the 8th International Conference on Bioinformatics models, Methods and Algorithms - Volume 3: BIOINFORMATICS, 21-23 February 2017, Porto, Portugal. SCITEPRESS Digital Library. pp 93-103. (Revue non indexée – (BIOSTEC 2017) (ISBN :978-989-758_214-1)
Miraglio B., Bernot G., Comet J.-P., Risso-de Faverney C. 2016 Towards a Computer Aided Toxicology. In: Proceedings of the Evry Spring School on Advances in Systems and Synthetic Biology, Modelling Complex Biological Systems in the Context of Genomics. Eds : P. Amar, F. Képès and V. Norris ; March 21st-25th 2016, Génopôle d’Evry, France. EDP Science. pp 85-101. (Revue non indexée - HAL Id :hal-01345025).
Mansour C., Risso-de Faverney C., Zrafi I.,Guibbolini M., Saidane-Mosbahi D. 2016. Oxidative stress and damage biomarkers in clam Ruditapes decussatus to assess pollution in the south lagoon of Tunis (Tunisia). Rapp. Commiss. int. Mer Médit., 41: 200.
Rouane-Hacene O., Boutiba Z., Risso C. 2016. La recherche des pesticides organochlorés dans les poissons marins : outil de biosurveillance de l’environnement marin et de suivi de la qualité sanitaire des produits de la pêche. Maison d'édition : Presses Académiques Francophones-245 pp. (ISBN:978-3-8416-3921-9)
Bernot G., Comet J.P., Risso-de Faverney C. 2013. Regulatory networks. In: Computational Toxicology Volume II. Methods in Molecular Biology. Eds: Reisfeld B. Mayeno A.N. ; Springer Science & Business Media published by Humana Press, USA.. Vol. 930:215-234. (ISBN: 978-1-62703-058-8 (Print) 978-1-62703-059-5 (Online))
Rouane-Hacene O., Boutiba Z., Risso C. 2013. Approche multibiomarqueurs appliquée à la biosurveillance marine. Suivi des indices biologiques et de la bioaccumulation métallique chez la moule et l'oursin. Maison d'édition : Presses Académiques Francophones-364 pp. (ISBN:978-3-8416-2254-9)
Risso-de Faverney C., de Sousa G., Lafaurie M., Rahmani, R., 2001. Inhibitory effects of heavy metals on CYP1A1 Induction in Black Seabream (Spondyliosoma Cantharus) hepatocyte cultures. In : Biomarkers in Marine Organisms : a practical approach. Eds : Garrigues Ph., Walter C.H., Barth H. ; Elsevier Science, The Netherlands, Japan. 16, 393-408. (ISBN: 978-0-444-82913-9)
Risso-de Faverney C., de Sousa G., Lafaurie M., Rahmani, R., 2001. Fish hepatocyte cultures. In : Biomarkers in Marine Organisms : a practical approach. Eds : Garrigues Ph., Walter C.H., Barth H. ; Elsevier Science, The Netherlands, Japan. 527-528. (ISBN: 978-0-444-82913-9)
Risso-de Faverney C., de Sousa G., Lafaurie M., Rahmani, R., 2001. Determination of cytochromes P450 expression and induction in black seabream (Spondyliosoma cantharus) : enzyme activities, Northern and Western blots. In : Biomarkers in Marine Organisms : a practical approach. Eds : Garrigues Ph., Walter C.H., Barth H. ; Elsevier Science, The Netherlands, Japan. 529-532. (ISBN: 978-0-444-82913-9)

Cours, résumé de PhD, etc.